MPowRX™ Snoring Solution Clinical Trial

A Randomized, Controlled, Crossover Study of the MPowRx™ Snoring Solution for Sleep Disordered Breathing Was Conducted by Calgary Dental Researcher, Dr. Leslie Dort (MSc, DDS, Dip ABDSM) and Published in the Journal of Sleep and Breathing, May 2008

A group of 32 patients were subjected to randomized, controlled cross-over study involving the MPowRx™ Snoring Solution and a control device of a similar design but without the suction mechanism. Patients used each device for one week, and were evaluated according to three standard industry measures of snoring: The Respiratory Disturbance Index (RDI), a measure of the number of sleep disturbances divided by the number of hours sleep; the Snoring Index, which measures the average number of snores per hour; and Epworth Sleepiness Scale (ESS), a measure of sleep propensity during the day as perceived by the subjects and derived from the answers to eight questions. All subjects had to have a primary diagnosis of snoring by a physician to participate in the study. The results of the study are summarized below:

• On average, RDI was reduced by at least 50% in 34% of subjects, resulting in a clinically significant reduction in the number of disturbances to less than 10 per hour. The definition of therapeutic success is a reduction in RDI to <10 per hour. Four out of five subjects with severe OSA (RDI>30), showed reduction in RDI of at least 50%.

• On average, the MPowRx Snoring Solution reduced the SI by at nearly 40%, achieving a significant improvement in night time snoring.

• The majority of subjects (>70%) wished to continue using the device because it improved their snoring or daytime sleepiness (high compliance).

This is the first and only randomized, controlled cross-over clinical study for these types of devices, establishing its scientific credibility and efficacy.

Dort LC, Hadjuk E, Remmers. JE Mandibular advancement and obstructive sleep apnea: a method for determining effective mandibular protrusion. European Respiratory Journal. 2006 May;27(5):1003-9. web-link

Dort LC and Brant R. A randomized, controlled, crossover study of a noncustomized tongue retaining device for sleep disordered breathing. Sleep and Breathing. 2008:  In Press

Dort LC, Hussein J. Snoring and obstructive sleep apnea: compliance with oral appliance therapy. Journal of  Otolaryngology. 2004; 33: p172 – 176 web-link

Tsai WH, Vazquez JC, Oshima T, Dort LC, Roycroft B, Lowe AA, Hajduk E, Remmers JE
Remotely controlled mandibular positioner predicts efficacy of oral appliances in sleep apnea. American Journal of  Respiratory Medicine and  Critical Care Medicine. 2004 ;170: p 366-370. web-link

Dort LC. When Patients Fall Asleep in the Dental Chair — A Wake-up Call for Dentists. Journal of the  Canadian Dental Association 2003; 69: p14–15  web-link

TESTIMONIAL

"Just wanted to say thank you - IT WORKS!

Four Nights  now and no snoring. My husband is estactic and I feel more rested...at last!"

- Jackie, a satisfied ex-snorer.

"Since purchasing the MPowRx anti-snoring device my husband and I can now fall asleep together. I am so pleased how it works, I no longer have to listen for hours before finally falling asleep to his loud snoring noises. Thanks for the great product, we both appreciate it"

-Keri, Wetaskiwin